Experimental cancer combo trial ends early – only 5 patients treated

NCT ID NCT06182579

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tested a drug called RiMO-401, injected directly into tumors and followed by radiation, in people with advanced cancers that had not responded to standard treatments. Only 5 patients were enrolled before the study was terminated. The main goal was to find a safe dose and check for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

RiMO-401 (a drug injected into the tumor, then activated by radiation)

What this could lead to

If it works, this could point toward a way to make radiation more effective for hard-to-treat tumors.

What could go wrong

This was a very early, small trial that was terminated early, so we have little data. It may not work or may cause unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Illinois at Chicago

    Chicago, Illinois, 60612, United States