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New pill cuts migraine days in half for many in major trial

NCT ID NCT05399485

Completed Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

Summary

This study tested whether a medication called rimegepant, taken regularly, could help prevent migraines in Japanese adults who get them frequently. Nearly 500 participants were randomly assigned to receive either rimegepant or a placebo pill for 12 weeks to see if it safely reduced the number of migraine days per month. The main goal was to see if the treatment group had fewer migraine days and a better quality of life compared to the placebo group.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Atago Hospital

    Kochi, Kochi, 780-0051, Japan

  • Atsuchi Neurosurgery Hospital

    Kagoshima, Kagoshima-ken, 892-0842, Japan

  • Doi Clinic Internal Medicine/Neurology

    Hiroshima, Hiroshima, 730-0031, Japan

  • Dokkyo Medical Univ. Hosp.

    Shimotsuga-gun, Tochigi, 321-0293, Japan

  • Fujitsu Clinic

    Nakahara, Kanagawa, 211-8588, Japan

  • Fukuuchi Pain Clinic

    Shinjuku-ku, Tokyo, 160-0017, Japan

  • Higashi Sapporo Neurology and Neurosurgery Clinic

    Sapporo, Hokkaido, 003-0003, Japan

  • Ikeda Neurosurgical Clinic

    Kasuga-shi, Fukuoka, 816-0824, Japan

  • Iwate Medical University Uchimaru Medical Center

    Morioka, Iwate, 020-8505, Japan

  • Japanese Red Cross Asahikawa Hospital

    Asahikawa-shi, Hokkaido, 070-8530, Japan

  • Japanese Red Cross Shizuoka Hospital

    Shizuoka, Shizuoka, 420-0853, Japan

  • Jinnouchi Neurosurgical Clinic

    Kasuga-shi, Fukuoka, 816-0802, Japan

  • Juntendo University Hospital

    Bunkyo-ku, Tokyo, 113-8431, Japan

  • Keio University Hospital

    Shinjuku-ku, Tokyo, 160-8582, Japan

  • Kijima Neurosurgery Clinic

    Kahoku-gun, Ishikawa-ken, 929-0342, Japan

  • Kindai University Hospital

    Osakasayama-shi, Osaka, 589-8511, Japan

  • Kitasato University Kitasato Institute Hospital

    Minato-ku, Tokyo, 108-8642, Japan

  • Konan Medical Center

    Higashinada-ku, Hyōgo, 658-0064, Japan

  • Makabe Clinic

    Okayama, Okayama-ken, 700-0964, Japan

  • Medical Corporation Seikokai Takanoko Hospital

    Matsuyama, Ehime, 790-0925, Japan

  • Medical Research Institute KITANO HOSPITAL, PIIF Tazuke-kofukai

    Osaka, Osaka, 530-8480, Japan

  • Mito Kyodo General Hospital

    Mito, Ibaraki, 310-0015, Japan

  • Nagamitsu Clinic

    Hofu-shi, Yamaguchi, 747-0802, Japan

  • Nagaseki Headache Clinic

    Kai-shi, Yamanashi, 400-0124, Japan

  • Nakamura Memorial Hospital

    Chūōku, Hokkaido, 060-8570, Japan

  • Nishinomiya Munic. Ctr. Hosp.

    Nishinomiya-shi, Hyōgo, 663-8014, Japan

  • Nishiogi Pain Clinic

    Suginami-ku, Tokyo, 167-0054, Japan

  • Okayama City General Medical Center Okayama City Hospital

    Okayama, Okayama-ken, 700-8557, Japan

  • Ooba Clinic for Neurosurgery & Headache

    Ōita, Oita Prefecture, 870-0831, Japan

  • SUBARU Health Insurance Society Ota Memorial Hospital

    Ota-shi, Gunma, 373-8585, Japan

  • Saiseikai Kumamoto Hospital

    Kumamoto, Kumamoto, 861- 4193, Japan

  • Saitama Medical University Hospital

    Iruma-gun, Saitama, 350-0495, Japan

  • Saitama Neuropsychiatric Institute

    Saitama-shi, Saitama, 338-8577, Japan

  • Sakura Neuro Clinic

    Toyama, Toyama, 930-0803, Japan

  • Sendai Headache and Neurology Clinic, Medical Corporation

    Sendai, Miyagi, 982-0014, Japan

  • Shinagawa Strings Clinic

    Minato-ku, Tokyo, 108-0075, Japan

  • St. Marianna Univ. Hospital

    Kawasaki-shi, Kanagawa, 216-8511, Japan

  • Takase Intern. Med. Clinic

    Toyonaka-shi, Osaka, 560-0012, Japan

  • Tanaka Neurosurgical Clinic

    Kagoshima, Kagoshima-ken, 892-0844, Japan

  • Tatsuoka Neurology Clinic

    Kyoto, Kyoto, 600-8811, Japan

  • Tokai univ. hachioji hosp.

    Hachioji-shi, Tokyo, 192-0032, Japan

  • Tominaga Clinic

    Osaka, Osaka, 556-0015, Japan

  • USUDA CLINIC for internal medicine

    Setagaya-ku, Tokyo, 156-0043, Japan

  • Umenotsuji Clinic

    Kochi, Kochi, 780-8011, Japan

Conditions

Explore the condition pages connected to this study.

MIGRAINE