Can a simple arm cuff save tiny intestines? new trial hopes to find out

NCT ID NCT05279664

First seen Feb 03, 2026 · Last updated May 20, 2026 · Updated 12 times

Summary

This study tests whether a technique called remote ischemic conditioning (RIC) can be used in newborns with a serious gut disease called necrotizing enterocolitis (NEC). RIC involves briefly inflating a blood pressure cuff on the baby's limb to protect the gut from damage. The goal is to see if it's possible to run a larger trial, not yet to prove it works. About 78 babies will be randomly assigned to receive RIC or standard care.

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Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Mount Sinai Hospital

    Toronto, Ontario, M5G 1X5, Canada

  • Sunnybrook Health Sciences Center

    Toronto, Ontario, M4Y 3M5, Canada

  • The Hospital for Sick Children

    Toronto, Ontario, M5G1X8, Canada

Conditions

Explore the condition pages connected to this study.