Cancer patients get continued access to promising drug

NCT ID NCT02934568

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study allows people with advanced cancers who are already benefiting from the drug ribociclib in a previous Novartis trial to keep receiving it. The goal is to provide continued access and monitor how long they stay on treatment and any side effects. Only 22 patients are enrolled, and they must be getting clinical benefit as judged by their doctor.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ribociclib (LEE011)

What this could lead to

If successful, this study allows patients with advanced cancers to keep receiving a treatment that is already working for them, potentially extending their benefit.

What could go wrong

This is a small rollover study (22 patients) with no control group, so results may not apply broadly. Side effects like liver issues or serious adverse events are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Broome Oncology

    Johnson City, New York, 13790, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Novartis Investigative Site

    Lyon, 69373, France

  • Novartis Investigative Site

    Villejuif, 94800, France

  • Novartis Investigative Site

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Novartis Investigative Site

    Singapore, 119228, Singapore

  • Novartis Investigative Site

    Madrid, 28041, Spain

  • Novartis Investigative Site

    Madrid, 28050, Spain

  • Novartis Investigative Site

    Tainan, 704302, Taiwan

  • Novartis Investigative Site

    Taipei, 10002, Taiwan

  • St Jude Childrens Research Hospital

    Memphis, Tennessee, 38105, United States

  • The Regents of the Uni of Michigan

    Ann Arbor, Michigan, 48109-5930, United States

  • University Of Alabama At Birmingham

    Birmingham, Alabama, 35294-3300, United States