Hormone cocktail aims to stop rare salivary cancer recurrence
NCT ID NCT06348264
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase 2 trial is testing whether a combination of rezvilutamide (a hormone-blocking pill) and standard hormone therapy can prevent high-risk salivary duct cancer from returning after surgery and radiation. About 37 participants with androgen receptor-positive cancer will receive the treatment for up to 2 years. The main goal is to see how many remain cancer-free after 3 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Rezvilutamide (a hormone-blocking drug) plus leuprolide acetate (a hormone therapy)
What this could lead to
If successful, this combination could offer a new way to lower the risk of cancer returning in people with high-risk salivary duct cancer.
What could go wrong
This is a small, early-phase trial with only 37 participants and no comparison group, so results may not be definitive. Hormone therapy can cause side effects like hot flashes, fatigue, and sexual changes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Peking University First Hospital
RECRUITINGBeijing, Beijing Municipality, 100034, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Peking University School and Hospital of Stomatology
RECRUITINGBeijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••