Promising new combo aims to extend life in rare, Tough-to-Treat cancer

NCT ID NCT07337447

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding two immunotherapy drugs (zimberelimab and domvanalimab) to standard chemotherapy (FOLFIRI) helps people with a rare, fast-growing neuroendocrine cancer live longer. About 122 adults whose cancer has worsened after first treatment will take part. The goal is to see if the combination improves survival at 12 months compared to chemotherapy alone.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neuroendocrine carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Amiens Picardie

    Amiens, France

    Contact

    Contact

  • CHU Avicenne APHP

    Bobigny, France

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    Contact

  • CHU Caen Normandie

    Caen, France

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    Contact

  • CHU Dijon

    Dijon, France

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    Contact

  • CHU Montpellier - Hôpital Saint Eloi

    Montpellier, France

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    Contact

  • CHU Rouen

    Rouen, France

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  • CHU Timone

    Marseille, France

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    Contact

  • CHU de Bordeaux - Hôpital Haut-Leveque

    Pessac, France

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    Contact

  • CHU de Grenoble

    Grenoble, France

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    Contact

  • CHU de Poitiers

    Poitiers, France

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    Contact

  • Centre Oscar Lambret

    Lille, France

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  • Centre Paul Strauss

    Strasbourg, France

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    Contact

  • HEGP

    Paris, France

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  • Hôpital Beaujon

    Clichy, France

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  • Hôpital Henri MONDOR

    Créteil, France

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  • Hôpital Robert Debré, CHU de Reims

    Reims, France

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    Contact

  • Hôpital Saint Antoine APHP

    Paris, France

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  • Hôpital Saint Louis APHP

    Paris, France

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  • Institut Gustave Roussy

    Villejuif, France

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  • Institut Paoli Calmettes

    Marseille, France

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    Contact

  • Service d'Oncologie Médicale - Hôpital Edouard Herriot - Hospices Civils de Lyon

    Lyon, France

    Contact

    Contact