New drug tested for Tough-to-Treat cancers after standard therapies fail

NCT ID NCT05731947

Summary

This early-phase study tested a new oral drug called revumenib (SNDX-5613) in 42 adults with advanced colorectal cancer or other solid tumors that had worsened despite at least one prior treatment. The main goals were to find a safe dose, see how the body processes the drug, and check for early signs that it might help control tumor growth. The study was completed and results will inform whether larger trials are warranted.

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Contacts and locations

Locations

  • Gabrail Cancer Center

    Canton, Ohio, 44718, United States

  • Honor Health Research Institute

    Scottsdale, Arizona, 85258, United States

  • Inova Schar Cancer Institute

    Fairfax, Virginia, 22031, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Memorial Sloan Kettering Cancer Center

    Manhattan, New York, 10065, United States

  • Vanderbilt-Ingram Cancer Center

    Nashville, Tennessee, 37232, United States

Conditions

Explore the condition pages connected to this study.