New hope for severe brain clots: clot removal plus meds vs. meds alone
NCT ID NCT07548346
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether removing blood clots from brain veins (endovascular thrombectomy) plus standard blood thinners works better than blood thinners alone for people with severe cerebral venous sinus thrombosis (CVST). The trial will include 440 adults at high risk of poor outcomes. The main goal is to see if the procedure helps more people live independently after 12 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Aga Khan University
Karachi, Pakistan
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Ain Shams University
Cairo, Egypt
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Alexandria University, Smouha Comprehensive Stroke Center
Alexandria, Egypt
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Amman Specialized IR Center
Amman, Jordan
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Cairo University
Cairo, Egypt
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Centre Hospitalier Universitaire Ibn Sina de Rabat
Rabat, Morocco
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Department of Neurology, Eskisehir Osmangazi University
Eskişehir, Turkey (Türkiye)
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Institut National de Neurologie
Tunis, Tunisia
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King Abdulaziz Medical City
Jeddah, Saudi Arabia
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King Abdullah Medical City
Mecca, Saudi Arabia
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King Khalid University
Abhā, Saudi Arabia
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Neurology Department, Al-Azhar University
Cairo, Egypt
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Neurology Department, Dr. Lutfi Kirdar City Hospital
Istanbul, Turkey (Türkiye)
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Weill Cornell Medicine-Qatar
Doha, Qatar
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Other studies related to the condition(s) this trial covers.