First safety check for liver drug in patients with failing kidneys

NCT ID NCT06397872

Summary

This early-stage study tested how a drug called resmetirom, which is being developed for liver disease, is processed by the body in people with severe kidney impairment. Researchers gave the drug for 6 days to 28 participants—half with severe kidney problems and half with healthy kidneys—to compare how their bodies handled it. The main goal was to see if the drug behaves differently in people with kidney disease and to check for safety issues.

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Contacts and locations

Locations

  • Madrigal Research Center

    Orlando, Florida, 32809, United States

  • Madrigal Research Center

    Tampa, Florida, 33603, United States

  • Madrigal Research Center

    Chicago, Illinois, 60643, United States

Conditions

Explore the condition pages connected to this study.