Exercise may counteract muscle loss from Gender-Affirming hormone therapy

NCT ID NCT07400419

First seen Feb 16, 2026 · Last updated May 29, 2026 · Updated 16 times

Summary

This study looks at whether a 12-week home resistance exercise program can help transgender women and gender-diverse people starting estrogen-based hormone therapy maintain muscle mass and strength. Estrogen therapy can reduce muscle and increase fat, raising the risk of a condition called sarcopenia. The study will compare an exercise group to a group receiving only advice, measuring changes in muscle and body composition.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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