Immune cell therapy shows promise for rare Muscle-Weakening disease

NCT ID NCT06359041

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 22 times

Summary

This early-phase study tests a new treatment called CABA-201 for people with generalized myasthenia gravis, a condition that causes muscle weakness. The therapy uses a patient's own immune cells, modified to target and destroy faulty immune cells that attack the body. The main goal is to check safety and see if it helps control the disease, though ongoing management may still be needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor College of Medicine Neurology Department

    Houston, Texas, 77030, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Columbia University

    New York, New York, 10032, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Mayo Clinic - Rochester

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic Florida

    Jacksonville, Florida, 32224, United States

  • Northwestern Memorial Hospital

    Chicago, Illinois, 60611, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Swedish Neuroscience Research

    Seattle, Washington, 98122, United States

  • UC Davis, Department of Neurology

    Sacramento, California, 95817, United States

  • University of California Irvine

    Orange, California, 92868, United States

  • University of California, San Francisco

    San Francisco, California, 94143, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Massachusetts Chan Medical School

    Worcester, Massachusetts, 01655, United States

  • University of Rochester Medical Center

    Rochester, New York, 14642, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.