New combo treatment aims to boost stroke recovery
NCT ID NCT04667078
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding a fast-acting blood thinner (cangrelor) to standard clot removal improves recovery in people with a severe stroke. About 368 adults with a large artery blockage in the brain will receive either cangrelor plus the procedure or the procedure alone. The main goal is to see if more patients have a good functional outcome (less disability) three months later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Cangrelor (a blood thinner given by IV)
What this could lead to
If it works, this could improve recovery and reduce disability after a severe stroke.
What could go wrong
This is a Phase 3 trial, but results are not guaranteed. Adding a blood thinner may increase bleeding risk, and the benefit may be small or absent.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU La Timone
RECRUITINGMarseille, 13005, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Besançon
RECRUITINGBesançon, 25030, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Strasbourg
RECRUITINGStrasbourg, 67200, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospices civils de Lyon, Hôpital Pierre Wertheimer
RECRUITINGBron, 69500, France
Contact Email: •••••@•••••
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Hôpital Central (CHU de Nancy)
RECRUITINGNancy, 54000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Dupuytren (CHU Limoges)
RECRUITINGLimoges, 87000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Foch
RECRUITINGSuresnes, 92150, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Fondation A de Rothschild
RECRUITINGParis, 75019, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Lariboisière AP-HP
RECRUITINGParis, 75010, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Pellegrin (CHU de Bordeaux)
RECRUITINGBordeaux, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Pitié-Salpêtrière AP-HP
RECRUITINGParis, 75013, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Purpan (CHU de Toulouse)
RECRUITINGToulouse, 31300, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Salengro (CHU Lille)
RECRUITINGLille, 59037, France
Contact Phone: •••-•••-•••• Email: •••••@•••••