New combo treatment aims to boost stroke recovery

NCT ID NCT04667078

Recruiting now Disease control Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a fast-acting blood thinner (cangrelor) to standard clot removal improves recovery in people with a severe stroke. About 368 adults with a large artery blockage in the brain will receive either cangrelor plus the procedure or the procedure alone. The main goal is to see if more patients have a good functional outcome (less disability) three months later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cangrelor (a blood thinner given by IV)
What this could lead to: If it works, this could improve recovery and reduce disability after a severe stroke.
What could go wrong: This is a Phase 3 trial, but results are not guaranteed. Adding a blood thinner may increase bleeding risk, and the benefit may be small or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ischemic disease ischemic stroke

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIA

Contacts and locations

Locations

CHU La Timone
RECRUITING

Marseille, 13005, France
CHU de Besançon
RECRUITING

Besançon, 25030, France
CHU de Strasbourg
RECRUITING

Strasbourg, 67200, France
Hospices civils de Lyon, Hôpital Pierre Wertheimer
RECRUITING

Bron, 69500, France
Hôpital Central (CHU de Nancy)
RECRUITING

Nancy, 54000, France
Hôpital Dupuytren (CHU Limoges)
RECRUITING

Limoges, 87000, France
Hôpital Foch
RECRUITING

Suresnes, 92150, France
Hôpital Fondation A de Rothschild
RECRUITING

Paris, 75019, France
Hôpital Lariboisière AP-HP
RECRUITING

Paris, 75010, France
Hôpital Pellegrin (CHU de Bordeaux)
RECRUITING

Bordeaux, France
Hôpital Pitié-Salpêtrière AP-HP
RECRUITING

Paris, 75013, France
Hôpital Purpan (CHU de Toulouse)
RECRUITING

Toulouse, 31300, France
Hôpital Salengro (CHU Lille)
RECRUITING

Lille, 59037, France

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