New hope for rare bone marrow cancer: reparixin trial targets those with few options
NCT ID NCT05835466
First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 37 times
Summary
This study tests whether the drug reparixin can help people with myelofibrosis, a serious bone marrow cancer. It is for patients with advanced disease who cannot take or refuse standard JAK inhibitor treatment. About 26 adults will take reparixin pills three times daily for 6 months, and may continue if their disease stays stable. The goal is to see if the drug can shrink the spleen, improve symptoms, or lead to remission.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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NewYork-Presbyterian/Weill Cornell Medical Center
RECRUITINGNew York, New York, 10065, United States
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Roswell Park Cancer Institute
RECRUITINGBuffalo, New York, 14263, United States
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Ruttenberg Treatment Center
RECRUITINGNew York, New York, 10029, United States
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The Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
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The Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
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Wake Forest Baptist Health Comprehensive Cancer Center
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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Conditions
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