New hope for rare bone marrow cancer: reparixin trial opens
NCT ID NCT05835466
First seen Nov 01, 2025 · Last updated Apr 24, 2026 · Updated 24 times
Summary
This study tests an oral drug called reparixin in 26 adults with myelofibrosis, a rare bone marrow cancer. Participants have advanced disease and cannot take or refuse standard JAK inhibitor treatment. The goal is to see if reparixin can shrink the spleen, improve blood counts, and ease symptoms over 6 months, with the option to continue if the disease stays stable.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Emory University
NOT_YET_RECRUITINGAtlanta, Georgia, 30322, United States
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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NewYork-Presbyterian/Weill Cornell Medical Center
RECRUITINGNew York, New York, 10065, United States
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Roswell Park Cancer Institute
RECRUITINGBuffalo, New York, 14263, United States
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Ruttenberg Treatment Center
RECRUITINGNew York, New York, 10029, United States
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The Cleveland Clinic Foundation
NOT_YET_RECRUITINGCleveland, Ohio, 44195, United States
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The Ohio State University
NOT_YET_RECRUITINGColumbus, Ohio, 43210, United States
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Wake Forest Baptist Health Comprehensive Cancer Center
RECRUITINGWinston-Salem, North Carolina, 27157, United States
Contact
Conditions
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