New heart valve study aims to improve survival in severe aortic stenosis

NCT ID NCT07414342

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing the RENATUS transcatheter aortic valve in 800 people with severe aortic stenosis, a condition where the heart's aortic valve narrows and makes it hard to pump blood. The valve is implanted through a catheter, avoiding open-heart surgery. Researchers are tracking how many patients survive over time and how well the procedure works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

RENATUS® Transcatheter Aortic Valve System (a device implanted via catheter to replace the aortic valve)

What this could lead to

If successful, this could confirm that the RENATUS valve is a safe and effective option for people with severe aortic stenosis, helping them live longer with fewer symptoms.

What could go wrong

This is an observational study, not a randomized trial, so results may be less definitive. Risks include complications from the procedure itself, such as bleeding or valve problems, and long-term outcomes are still being tracked.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Anzhen Hospital, Capital Medical University

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing Chaoyang Hospital, Capital Medical University

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Fu Wai Hospital, Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••