New heart valve study aims to improve survival in severe aortic stenosis

NCT ID NCT07414342

Recruiting now Disease control Sponsor: Beijing Balance Medical Technology Co., Ltd Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing the RENATUS transcatheter aortic valve in 800 people with severe aortic stenosis, a condition where the heart's aortic valve narrows and makes it hard to pump blood. The valve is implanted through a catheter, avoiding open-heart surgery. Researchers are tracking how many patients survive over time and how well the procedure works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: RENATUS® Transcatheter Aortic Valve System (a device implanted via catheter to replace the aortic valve)
What this could lead to: If successful, this could confirm that the RENATUS valve is a safe and effective option for people with severe aortic stenosis, helping them live longer with fewer symptoms.
What could go wrong: This is an observational study, not a randomized trial, so results may be less definitive. Risks include complications from the procedure itself, such as bleeding or valve problems, and long-term outcomes are still being tracked.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEVERE AORTIC STENOSIS

Contacts and locations

Locations

Beijing Anzhen Hospital, Capital Medical University
RECRUITING

Beijing, China
Beijing Chaoyang Hospital, Capital Medical University
RECRUITING

Beijing, China
Fu Wai Hospital, Chinese Academy of Medical Sciences
RECRUITING

Beijing, China
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
RECRUITING

Beijing, China

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