New sedative shows promise for Long-Term ICU sedation

NCT ID NCT05913336

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tested a sedative called remimazolam tosilate in 24 ICU patients who needed to be on a breathing machine for at least three days. The goal was to see if the drug could keep patients at the right sedation level safely. Because this is a small, non-randomized study, the results are preliminary and more research is needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

remimazolam tosilate

What this could lead to

If successful, this could provide a safer or more controllable sedation option for ICU patients who need to be on a breathing machine for days.

What could go wrong

This is a very early, small study (24 people) with no comparison group, so results may not apply broadly. The drug may not work as well as current sedatives or could have unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Affiliated Hospital of Guizhou Medical University

    Guiyang, Guizhou, 550001, China