New pill aims to tame painful skin disease in major trial

NCT ID NCT06799000

Recruiting now Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing whether an oral medication called remibrutinib can safely reduce painful skin lesions in people with moderate to severe hidradenitis suppurativa (HS). About 555 participants aged 12 and older will take either one of two doses of the drug or a placebo pill for 68 weeks. The main goal is to see if the medication can cut the number of painful abscesses and nodules in half by week 16.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Advanced Research Experts
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Nashville, Tennessee, 37211, United States

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Arkansas Research Trials
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North Little Rock, Arkansas, 72117, United States

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Bellaire Dermatology Associates
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Bellaire, Texas, 77401, United States

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Care Access Hoboken
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Hoboken, New Jersey, 07030, United States

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Cheryl Effron MD Inc
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Anaheim, California, 92807, United States

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Clinical Trials Research Institute
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Thousand Oaks, California, 91320, United States

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Dawes Fretzin Clinical Rea Group
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Indianapolis, Indiana, 46256, United States

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Dermat. and Adv. Aesthetics
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Lake Charles, Louisiana, 70605, United States

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Equity Medical LLC
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Bowling Green, Kentucky, 42104, United States

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Essential Medical Research
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Tulsa, Oklahoma, 74137, United States

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Florida Academic Centers Research and Education LLC
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Coral Gables, Florida, 33134, United States

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Forest Hills Dermatology Group
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New York, New York, 10003, United States

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Gwinnett Clinical Research Center
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Snellville, Georgia, 30078, United States

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Henry Ford Hospital
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Detroit, Michigan, 48202-2689, United States

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Howard University College of Medicine
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Washington D.C., District of Columbia, 20060, United States

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Icahn School Of Med At Mount Sinai
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New York, New York, 10029, United States

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Illinois Dermatology Institute
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Chicago, Illinois, 60602, United States

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Immunology-Rheumatology Research
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Suwanee, Georgia, 30024, United States

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Johnson Dermatology
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Fort Smith, Arkansas, 72916, United States

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Medical Dermatology Specialists
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Phoenix, Arizona, 85006, United States

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Medical University of South Carolina MUSC
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Charleston, South Carolina, 29425, United States

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Michigan Center for Rsrch Company
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Clarkston, Michigan, 48346, United States

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Novartis Investigative Site
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Caba, Buenos Aires, C1119ACN, Argentina
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CABA, Buenos Aires, C1425BEA, Argentina
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Rosario, Santa Fe Province, 2000, Argentina
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CABA, C1428DZF, Argentina
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Phillip, Australian Capital Territory, 2606, Australia
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Sydney, New South Wales, 2010, Australia
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Westmead, New South Wales, 2145, Australia
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Melbourne, Victoria, 3004, Australia
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Parkville, Victoria, 3050, Australia
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Pleven, 5800, Bulgaria
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Sofia, 1407, Bulgaria
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Stara Zagora, 6000, Bulgaria
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Surrey, British Columbia, V3V 0C6, Canada
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St. John's, Newfoundland and Labrador, A1E 1V4, Canada
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Hamilton, Ontario, L8L 3C3, Canada
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Richmond Hill, Ontario, L4C 9M7, Canada
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Québec, Quebec, G1W 4R4, Canada
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Saint-Jérôme, Quebec, J7Z 7E2, Canada
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Fuzhou, Fujian, 350025, China
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Guangzhou, Guangdong, 510000, China
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Wuhan, Hubei, 430022, China
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Changsha, Hunan, 410008, China
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Changchun, Jilin, 130021, China
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Shenyang, Liaoning, 110011, China
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Xian, Shanxi, 710004, China
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Chengdu, Sichuan, 610041, China
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Ürümqi, Xinjiang, 830001, China
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Ningbo, Zhejiang, 315016, China
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Beijing, 100144, China
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Jinan, 250012, China
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Barranquilla, Atlántico, 080002, Colombia
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Bogota, Cundinamarca, 110221, Colombia
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Cali, Valle del Cauca Department, 760032, Colombia
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Medellín, 050034, Colombia
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Kobenhavn N V, 2400, Denmark
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Roskilde, 4000, Denmark
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Langenau, Baden-Wurttemberg, 89129, Germany
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Darmstadt, Hesse, 64283, Germany
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Stade, Lower Saxony, 21682, Germany
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Dresden, Saxony, 01307, Germany
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Halle, Saxony-Anhalt, 06108, Germany
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Aachen, 52074, Germany
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Berlin, 10789, Germany
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Berlin, 13353, Germany
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Bochum, 44791, Germany
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Bonn, 53105, Germany
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Erlangen, 91054, Germany
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Hamburg, 20095, Germany
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Hanover, 30159, Germany
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Kiel, 24105, Germany
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Mainz, 55131, Germany
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Memmingen, 87700, Germany
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Münster, 48149, Germany
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Chaïdári, 124 62, Greece
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Heraklion Crete., 715 00, Greece
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Thessaloniki, 546 43, Greece
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Ancona, AN, 60126, Italy
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Brescia, BS, 25123, Italy
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Catania, CT, 95123, Italy
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Cona, FE, 44124, Italy
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Florence, FI, 50122, Italy
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Milan, MI, 20122, Italy
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Rozzano, MI, 20089, Italy
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Modena, MO, 41124, Italy
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Pisa, PI, 56126, Italy
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Roma, RM, 00168, Italy
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Torino, TO, 10126, Italy
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Muar town, Johor, 84000, Malaysia
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Kota Bharu, Kelantan, 15586, Malaysia
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George Town, Pulau Pinang, 10450, Malaysia
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Kuching, Sarawak, 93586, Malaysia
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Kuala Terengganu, Terengganu, 20400, Malaysia
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Kuala Lumpur, 59100, Malaysia
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Guadalajara, Jalisco, 44340, Mexico
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Guadalajara, Jalisco, 44650, Mexico
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Cuauhtémoc, Mexico City, 06100, Mexico
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Chihuahua City, 31203, Mexico
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Bydgoszcz, 85-094, Poland
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Gdansk, 80-214, Poland
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Lodz, 90-436, Poland
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Almada, 2805-267, Portugal
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Braga, 4710243, Portugal
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Coimbra, 3004-561, Portugal
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Lisbon, 1169-050, Portugal
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Lisbon, 1998-018, Portugal
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Porto, 4099-001, Portugal
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Bratislava, 811 09, Slovakia
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Bratislava, 813 69, Slovakia
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Prešov, 080 01, Slovakia
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Trnava, 917 02, Slovakia
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Raslouw Centurion, Gauteng, 0157, South Africa
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Soweto, Gauteng, 2013, South Africa
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Cape Town, 7505, South Africa
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Durban, 4058, South Africa
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Cadiz, Andalusia, 11009, Spain
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Badalona, Barcelona, 08916, Spain
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Sabadell, Barcelona, 08208, Spain
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Barcelona, Catalonia, 08003, Spain
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Manises, Valencia, 46940, Spain
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Valencia, Valencia, 46017, Spain
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Madrid, 28009, Spain
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Madrid, 28046, Spain
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Valencia, 46014, Spain
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Basel, 4031, Switzerland
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Bern, 3010, Switzerland
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Zurich, 8091, Switzerland
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Kaohsiung City, 83301, Taiwan
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Taipei, 10002, Taiwan
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Taoyuan District, 33305, Taiwan
Olive View UCLA Medical Center
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Sylmar, California, 91342, United States

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OnSite Clinical Solutions LLC
RECRUITING

Huntersville, North Carolina, 28078, United States

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Physioseq
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Sacramento, California, 95826, United States

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RFSA Dermatology
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San Antonio, Texas, 78213, United States

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Revival Research Institute
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Troy, Michigan, 48084, United States

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Revival Research Institute LLC
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Evans, Georgia, 30809, United States

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Skinsearch of Rochester Inc
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Rochester, New York, 14623, United States

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UP Medical Center H System
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Pittsburgh, Pennsylvania, 15213-3403, United States

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Unity Clinical Research
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Oklahoma City, Oklahoma, 73118, United States

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University of MiamiHealth System
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Miami, Florida, 33125, United States

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University of Mississippi Med Ctr
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Jackson, Mississippi, 39216, United States

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Virginia Clinical Research
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Norfolk, Virginia, 23507, United States

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Wake Forest Baptist Health
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Winston-Salem, North Carolina, 27104, United States

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Ziaderm Research LLC
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North Miami Beach, Florida, 33162, United States

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Conditions

Explore the condition pages connected to this study.

HIDRADENITIS SUPPURATIVA