New pill combo aims to melt heart plaque in High-Risk patients

NCT ID NCT06305559

First seen Apr 12, 2026 · Last updated May 14, 2026 · Updated 4 times

Summary

This study tests whether a daily pill combining obicetrapib and ezetimibe can reduce fatty plaque buildup in the heart arteries of 300 adults with high-risk heart disease. Participants must already be on maximum tolerated cholesterol medication and have significant plaque visible on a CT scan. The treatment is taken long-term to control disease, not cure it.

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Contacts and locations

Locations

  • NGMR

    Hialeah, Florida, 33016, United States

Conditions

Explore the condition pages connected to this study.