New Three-Drug cocktail targets tough leukemia

NCT ID NCT06454409

First seen Nov 19, 2025 · Last updated May 17, 2026 · Updated 20 times

Summary

This early-stage trial tests whether adding regorafenib to the standard venetoclax plus azacitidine regimen is safe and effective for adults with acute myeloid leukemia (AML) that has returned or not responded to prior treatment. About 20 participants will receive the combination to find the best dose and check for side effects. The goal is to control the disease, not cure it, as ongoing management is expected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.