Early trial halted for rare blood disease treatment
NCT ID NCT04409080
Summary
This early-stage study tested an experimental antibody called REGN7257 in people with severe aplastic anemia, a serious bone marrow disease where the body stops making enough blood cells. The trial focused on patients whose disease did not respond to or came back after standard immune-suppressing treatments. The main goals were to check the drug's safety, how it behaves in the body, and whether it could help increase patients' blood counts and reduce their need for blood transfusions.
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Contacts and locations
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Locations
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Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
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Ewha Womans University Medical Centre
Seoul, Seoul Capital Area, 07985, South Korea
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Gachon University Gil Hospital
Incheon, Gyeonggi-do, 21565, South Korea
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Hopital Saint-Louis - APHP
Paris, Île-de-France Region, 75010, France
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King's College Hospital, London
London, SE5 9RS, United Kingdom
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Samsung Medical Center
Seoul, Seoul Capital Area, 06351, South Korea
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Seoul National University Hospital
Seoul, Seoul Capital Area, 03080, South Korea
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St James's University Hospital
Leeds, West Yorkshire, LS97TF, United Kingdom
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The Catholic University of Korea, Seoul St. Marys Hospital
Seoul, Seoul Capital Area, 06591, South Korea
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
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