Experimental lung cancer drug trial halted early

NCT ID NCT04982224

First seen Nov 03, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This study tested an experimental drug, REGN5093-M114, for people with advanced non-small cell lung cancer that has too much MET protein. The goal was to find a safe dose and see if the drug could shrink tumors, either alone or with another drug called cemiplimab. The study was terminated early, but it involved about 30 participants and focused on safety and side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Henry Ford Hospital, Henry Ford Cancer Institute

    Detroit, Michigan, 48202, United States

  • Johns Hopkins Hospital - Clinical Study Location - Skip Viragh Outpatient Cancer Building

    Baltimore, Maryland, 21231, United States

  • MUSC Hollings Cancer Center

    Charleston, South Carolina, 29425, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Next Virginia

    Fairfax, Virginia, 22031, United States

  • Sidney Kimmel Comprehensive Cancer Center - 4F Second Medical Building

    Baltimore, Maryland, 21231, United States

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • University of California Irvine School of Medicine - Suite 400, Room 407

    Orange, California, 92868, United States

  • University of Colorado Hospital Anshutz Outpatient Pavillion

    Denver, Colorado, 80045, United States

  • University of Pittsburgh Medical Center - Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

Conditions

Explore the condition pages connected to this study.