Promising drug for rare fat disorder trial halted early
NCT ID NCT05088460
First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 22 times
Summary
This study tested a drug called REGN4461 in people with familial partial lipodystrophy, a rare condition where fat is distributed abnormally, leading to serious metabolic issues like high triglycerides and diabetes. The trial aimed to see if the drug could improve blood fat and sugar levels. It was terminated early, so results are limited.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Complexo Hospitalario Universitario de Santiago-Hospital Médico-Cirúrxico de Conxo
Santiago de Compostela, Galicia, 15706, Spain
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Ege University Faculty of Medicine
Izmir, Bornova, 35100, Turkey (Türkiye)
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Excel Medical Clinical Trials - A Flourish Research Site
Boca Raton, Florida, 33434, United States
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ICAN, Institute of Cardiometabolism and Nutrition
Paris, 75013, France
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National Institute of Health
Bethesda, Maryland, 20892, United States
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UT Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of Michigan
Ann Arbor, Michigan, 48109, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
Conditions
Explore the condition pages connected to this study.