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Study investigates whether more nerve blocks mean better recovery for polytrauma patients

NCT ID NCT07702071

Knowledge-focused Sponsor: Ukrainian Society of Regional Anesthesia and Pain Therapy Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study looks at severely injured adults with multiple traumatic injuries who receive one or more nerve blocks for pain. Researchers want to see if having more blocks improves pain control, reduces opioid use, and helps patients regain mobility faster, or if it increases risks. The goal is to find the best balance of pain relief and safety for these complex patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors decide how many nerve blocks are safe and effective for severe trauma patients, potentially improving pain control and recovery.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to all trauma settings or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of consecutive adult patients with polytrauma admitted to a Level I trauma center who receive one or more ultrasound-guided peripheral nerve blocks and/or continuous peripheral nerve catheters as part of routine multimodal pain management. Patients will be managed according to institutional trauma and regional anesthesia protocols. Prospective clinical data will be collected to evaluate the relationship between Regional Anesthesia Burden and pain control, opioid consumption, functional recovery, regional anesthesia-related complications, and early clinical outcomes during hospitalization and at 3-month follow-up.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years or older. * Diagnosis of polytrauma, defined as traumatic injuries involving two or more anatomical regions. * Injury Severity Score (ISS) ≥16. * Hospital admission within 48 hours after injury. * Requirement for acute pain management during hospital treatment. * Receipt of at least one ultrasound-guided peripheral nerve block and/or continuous peripheral nerve catheter as part of routine clinical care. * Ability to collect clinical data on regional anesthesia procedures, analgesic use, pain assessment, and early recovery outcomes. * Written informed consent provided by the patient or legally authorized representative, according to local regulations. Exclusion Criteria: * Age younger than 18 years. * Isolated single-system injury without polytrauma. ISS \<16. * Expected survival less than 24 hours after admission. * Severe traumatic brain injury or impaired consciousness preventing reliable pain and functional assessment, unless validated behavioral pain scales can be used. * Known allergy or contraindication to local anesthetics. * Pre-existing severe neuromuscular disease affecting motor function assessment. * Chronic opioid therapy before injury. * Pregnancy. * Enrollment in another interventional trial that may affect pain management or functional recovery outcomes. * Missing essential data required for assessment of Regional Anesthesia Burden.

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Conditions

The condition(s) this trial relates to.

Acute Pain combat disorder Multiple Trauma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute pain Combat trauma Nerve block Polytrauma Regional anaesthesia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Vinnitsya university hospital

    Vinnytsia, 21000, Ukraine

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