New device aims to quiet chronic chest pain

NCT ID NCT02710435

Ongoing Symptom relief Sponsor: Shockwave Medical, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a device called the Neovasc Reducer in 400 people with chronic stable angina who have not found relief from standard treatments. The device is implanted to improve blood flow and reduce chest pain. Researchers will track symptom improvement and any serious side effects over several years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Neovasc Reducer device
What this could lead to: If successful, this device could offer a new way to reduce chest pain in people with chronic angina who have few other treatment options.
What could go wrong: This is an observational study, not a controlled trial, so results may be less definitive. The device also carries risks like heart attack or arrhythmia.

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Conditions

The condition(s) this trial relates to.

Angina Pectoris Angina, Stable intermediate coronary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANGINA PECTORIS ANGINA PECTORIS, STABLE CHRONIC STABLE ANGINA

Contacts and locations

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Locations

Bolognini General Hospital

Seriate, 24068, Italy
Bradford Royal Infirmary

Bradford, BD9 6RJ, United Kingdom
Contilia Heart and Vascular Centre, Elisabeth Krankenhaus Essen, Klinik fϋr Kardiologie und Angiologie

Essen, 45138, Germany
Dresden University

Dresden, 01307, Germany
HFR Fribourg/University of Fribourg

Fribourg, 1708, Switzerland
Hopitaux Universitaires Geneve (HUG)

Geneva, 1205, Switzerland
Hospital Clinico San Carlos

Madrid, 28040, Spain
Institut Coeur Poumon

Lille, France
Istituto Cardiocentro Ticino

Lugano, 6900, Switzerland
Kerckhoff Klinik

Bad Nauheim, 61231, Germany
King's College Hospital

London, SE5 9RS, United Kingdom
Royal Brompton Hospital

London, SW3 6NP, United Kingdom
Royal Infirmary of Edinburgh

Edinburgh, EH16 4SA, United Kingdom
San Raffaele Hospital

Milan, 20132, Italy
St. Antonius Ziekenhuis

Nieuwegein, 3435CM, Netherlands
St. Thomas Hospital

London, SE1 7EH, United Kingdom
UMC Utrecht

Utrecht, 3584 CX, Netherlands
University Giessen

Giessen, 35392, Germany
University Heart Center Freiburg - Bad Krozingen

Freiburg im Breisgau, 79106, Germany
University Heart Center Hamburg

Hamburg, 20246, Germany
University Hospital Basel

Basel, CH-4031, Switzerland
University Hospital of Brest

Brest, France
University of Graz

Graz, 8010, Austria
ZNA Middelheim Hospital

Antwerp, 2020, Belgium
Zienkenhuis Oost-Limburg

Genk, 3600, Belgium

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