Could a lower drug dose make stem cell transplants safer for blood cancer patients?

NCT ID NCT07193420

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 37 times

Summary

This study tests if a lower dose of a drug called cyclophosphamide can reduce side effects after a stem cell transplant from a half-matched donor in people with blood cancers. About 180 adults will be randomly assigned to receive either the standard or a reduced dose. The goal is to see if the lower dose improves survival without severe graft-versus-host disease, relapse, or drug-related problems over two years.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Saint Antoine Hospital - Hematology Department

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

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