Could a lower drug dose make stem cell transplants safer for blood cancer patients?

NCT ID NCT07193420

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 43 times

Summary

This study tests whether giving a lower dose of a drug called cyclophosphamide after a stem cell transplant can reduce side effects while still preventing graft-versus-host disease (GVHD) and cancer relapse. The trial involves 180 adults with blood cancers who are receiving a half-matched (haploidentical) stem cell transplant. The goal is to see if the lower dose improves survival without severe complications two years after the transplant.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Saint Antoine Hospital - Hematology Department

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

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