Could less radiation be enough for some lymphoma patients?
NCT ID NCT07628738
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looks at whether a lower dose of radiation can safely prevent cancer from returning in people with early-stage nasal-type NK/T-cell lymphoma who have already had a complete response to chemotherapy. Participants receive 45 Gy of radiation over five weeks, targeting the original tumor area and nearby lymph nodes. The main goal is to see how many patients remain free of local or regional recurrence two years after treatment.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- reduced-intensity radiotherapy
- What this could lead to
- If successful, this approach could offer a less toxic radiation option for certain lymphoma patients, potentially reducing side effects while maintaining cancer control.
- What could go wrong
- This is a small, early-phase study (39 participants) with no control group, so results may not be definitive. The reduced radiation might be less effective at preventing recurrence than standard doses.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
RECRUITINGShanghai, Shanghai Municipality, 200025, China