Could less radiation be enough? new trial for advanced throat cancer

NCT ID NCT07328841

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people with advanced nasopharyngeal cancer (a type of throat cancer) whose tumors shrank significantly after initial chemotherapy and immunotherapy. It compares a lower dose of radiation therapy to the standard dose, both given with additional chemo and immunotherapy. The goal is to see if the lower dose is just as effective at preventing cancer from coming back while causing fewer side effects. About 456 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma Pathologic Complete Response

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Center of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

  • Cancer Hospital of Shantou University Medical College

    RECRUITING

    Shantou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Central South University Cancer Hospital

    RECRUITING

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sun Yat-sen University cancer center

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Fifth Affiliated Hospital of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, 516000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Fifth Affiliated Hospital of Sun Yat-sen University

    RECRUITING

    Guangdong, Zhuhai, 519000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The People's Hospital of Guangxi Zhuang Autonomous Region

    RECRUITING

    Nanning, Guangxi, 530021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Sun Yat-sen University (SYSU)

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Phone: •••-•••-••••

  • Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-••••

  • Wuzhou Red Cross Hospital

    RECRUITING

    Wuzhou, Guangxi, China

    Contact Phone: •••-•••-••••

  • Xiangya Hospital of Central South University

    RECRUITING

    Changsha, Hunan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zhongshan City People's Hospital

    RECRUITING

    Zhongshan, Guangdong, China

    Contact Phone: •••-•••-••••