Could less radiation be enough? new trial for advanced throat cancer

NCT ID NCT07328841

Recruiting now Disease control Sponsor: Ming-Yuan Chen Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people with advanced nasopharyngeal cancer (a type of throat cancer) whose tumors shrank significantly after initial chemotherapy and immunotherapy. It compares a lower dose of radiation therapy to the standard dose, both given with additional chemo and immunotherapy. The goal is to see if the lower dose is just as effective at preventing cancer from coming back while causing fewer side effects. About 456 participants will be enrolled.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma Pathologic Complete Response

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NASOPHARYNGEAL CARCINOMA (NPC)

Contacts and locations

Locations

Cancer Center of Guangzhou Medical University
RECRUITING

Guangzhou, Guangdong, China
Cancer Hospital of Shantou University Medical College
RECRUITING

Shantou, Guangdong, China
Central South University Cancer Hospital
RECRUITING

Changsha, Hunan, China
Sun Yat-sen University cancer center
RECRUITING

Guangzhou, Guangdong, China
The Fifth Affiliated Hospital of Guangzhou Medical University
RECRUITING

Guangzhou, Guangdong, 516000, China
The Fifth Affiliated Hospital of Sun Yat-sen University
RECRUITING

Guangdong, Zhuhai, 519000, China
The People's Hospital of Guangxi Zhuang Autonomous Region
RECRUITING

Nanning, Guangxi, 530021, China
The Second Affiliated Hospital of Sun Yat-sen University (SYSU)
RECRUITING

Guangzhou, Guangdong, China
Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, China
Wuzhou Red Cross Hospital
RECRUITING

Wuzhou, Guangxi, China
Xiangya Hospital of Central South University
RECRUITING

Changsha, Hunan, China
Zhongshan City People's Hospital
RECRUITING

Zhongshan, Guangdong, China

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