Could less chemo after transplant mean better survival?

NCT ID NCT07193420

First seen Nov 01, 2025 · Last updated Apr 28, 2026 · Updated 32 times

Summary

This study tests whether a lower dose of a chemotherapy drug (cyclophosphamide) given after a half-matched stem cell transplant can help people with blood cancers live longer without severe complications. About 180 adults will be randomly assigned to receive either the standard dose or a reduced dose. The goal is to see if the lower dose reduces side effects while still preventing graft-versus-host disease and cancer relapse.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Saint Antoine Hospital - Hematology Department

    Paris, 75012, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

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