Could a lower dose of this heart drug be safer and just as effective?

NCT ID NCT07273994

First seen Jan 11, 2026 · Last updated May 29, 2026 · Updated 20 times

Summary

This study looks at whether a lower daily dose of the heart medication amiodarone (100 mg) can keep the heart in normal rhythm as well as the standard dose (200 mg) after an electrical shock procedure for persistent atrial fibrillation. About 312 adults with this condition will take the full dose for one month, then be randomly assigned to continue the full dose or switch to the lower dose. The goal is to find a dose that works well but causes fewer side effects over a year.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PERSISTENT ATRIAL FIBRILLATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hospital de la Santa Creu i Sant Pau

    RECRUITING

    Barcelona, 08025, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.