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Can a second keyhole valve replacement work? new study aims to find out

NCT ID NCT06557798

Recruiting now Disease control Sponsor: The Leeds Teaching Hospitals NHS Trust Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 29 times

Summary

This study follows 550 people whose TAVI heart valve has stopped working properly. Researchers will track how well a second TAVI procedure works, including safety and long-term results. The goal is to help doctors decide the best way to treat patients with a failed TAVI valve.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aalborg Universitethospital

    RECRUITING

    Aalborg, Denmark

  • Amphia Hospital

    RECRUITING

    Breda, Netherlands

  • Asklepios Klinik St. Georg

    RECRUITING

    Hamburg, Germany

  • Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele

    RECRUITING

    Catania, Italy

  • Brest University Hospital Centre

    RECRUITING

    Brest, France

  • Bristol Royal Infirmary

    RECRUITING

    Bristol, United Kingdom

  • CHRU Hospitals of Tours

    RECRUITING

    Tours, France

  • Centre Hospitalier Universitaire de Montpellier

    RECRUITING

    Montpellier, France

  • Centro Cardiologico Monzino

    RECRUITING

    Milan, Italy

  • Clinical Saint Augustin - Elsan

    RECRUITING

    Bordeaux, France

  • Clinique Pasteur Toulouse

    RECRUITING

    Toulouse, France

  • Erasmus University Medical Center

    RECRUITING

    Rotterdam, Netherlands

  • Freeman Hospital

    RECRUITING

    Newcastle upon Tyne, United Kingdom

  • Glenfield Hospital

    RECRUITING

    Leicester, United Kingdom

  • Golden Jubilee National Hospital

    RECRUITING

    Glasgow, United Kingdom

  • Guys and St Thomas' NHS Foundation Trust

    RECRUITING

    London, United Kingdom

  • HELIOS Herzzentrum Leipzig GmbH

    RECRUITING

    Leipzig, Germany

  • HUS Helsinki University Hospital

    RECRUITING

    Helsinki, Finland

  • Haukeland Sykehus

    RECRUITING

    Bergen, Norway

  • Henri Mondor University Hospital

    RECRUITING

    Créteil, France

  • Herz- und Diabeteszentrum NRW

    RECRUITING

    Bad Oeynhausen, Germany

  • Herzzentrum Dresden Universitätsklinik

    RECRUITING

    Dresden, Germany

  • Hospital Marie Lannelongue

    RECRUITING

    Paris, France

  • ICPS Hôpital privé Jacques-Cartier

    RECRUITING

    Massy, France

  • IRCCS Ospedale San Raffaele

    RECRUITING

    Milan, Italy

  • IRCSS Policlinico San Donato

    RECRUITING

    San Donato Milanese, Italy

  • Inselspital - Universitätsspital Bern

    RECRUITING

    Bern, Switzerland

  • Institute Mutualiste Montsouris

    RECRUITING

    Paris, France

  • Kerckhoff Klinik

    RECRUITING

    Bad Nauheim, Germany

  • Klinikum Dortmund GmbH - St. Johannes Hospital

    RECRUITING

    Dortmund, Germany

  • LMU Klinikum

    RECRUITING

    München, Germany

  • Leeds Teaching Hospitals NHS Trust

    RECRUITING

    Leeds, LS1 3EX, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Les Hospital Universitaires de Strasbourg

    RECRUITING

    Strasbourg, France

  • Luzerner Kantonsspital

    RECRUITING

    Lucerne, Switzerland

  • Maastricht University Medical Center (MUMC)

    RECRUITING

    Maastricht, Netherlands

  • Manchester Royal Infirmary

    RECRUITING

    Manchester, United Kingdom

  • Medipole Lyon-Villeurbanne

    RECRUITING

    Villeurbanne, France

  • New Cross Hospital

    RECRUITING

    Wolverhampton, United Kingdom

  • Nya Karolinska Sjukhuset Solna

    RECRUITING

    Solna, Sweden

  • Oslo University Hospital

    RECRUITING

    Oslo, Norway

  • Ospedale Borgo Trento - Azienda Ospedaliera Universitaria Integrata Verona

    RECRUITING

    Verona, Italy

  • Ospedale San Martino - IRCCS Ospedale Policlinico

    RECRUITING

    Genova, Italy

  • Oxford University Hospitals NHS Foundation Trust

    RECRUITING

    Oxford, OX3 9DU, United Kingdom

  • Queen Elizabeth Hospital

    RECRUITING

    Birmingham, United Kingdom

  • Rabin Medical Center - Belinson Campus

    RECRUITING

    Petah Tikva, Israel

  • Rigshospitalet

    RECRUITING

    Copenhagen, Denmark

  • Royal Sussex County Hospital

    RECRUITING

    Brighton, BN2 1ES, United Kingdom

  • Sahlgrenska University Hospital

    RECRUITING

    Gothenburg, Sweden

  • Shaare Zedek Medical Center

    RECRUITING

    Jerusalem, Israel

  • Skånes Universitetssjukhus Lund

    RECRUITING

    Lund, Sweden

  • St. George's Hospital

    RECRUITING

    London, United Kingdom

  • Turku University Hospital

    RECRUITING

    Turku, Finland

  • Universitatsklinikum Dusseldorf (University Hospital Dusseldorf)

    RECRUITING

    Düsseldorf, Germany

  • Universitatsklinikum Frankfurt

    RECRUITING

    Frankfurt, Germany

  • Universitatsklinikum Ulm (University Hospital Ulm)

    RECRUITING

    Ulm, Germany

  • University Hospital Southampton NHS Foundation Trust

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

  • University Hospital of Nimes

    RECRUITING

    Nîmes, France

  • University Hospital of Wales

    RECRUITING

    Cardiff, CF14 4XW, United Kingdom

  • Universitätsklinikum Schleswig-Holstein (UKSH)

    RECRUITING

    Kiel, Germany

  • Universitätsklinikum Schleswig-Holstein (UKSH)

    RECRUITING

    Lübeck, Germany

  • Århus Universitetshospital

    RECRUITING

    Aarhus, Denmark

Conditions

Explore the condition pages connected to this study.

AORTIC VALVE STENOSIS