Could less radiation mean fewer side effects for anal cancer patients?

NCT ID NCT05902533

Ongoing Symptom relief Sponsor: University of Cincinnati Source: ClinicalTrials.gov ↗

First seen Jan 04, 2026 · Last updated May 23, 2026 · Updated 25 times

Summary

This study is testing whether giving a lower dose of radiation to nearby lymph nodes during standard chemoradiation for anal cancer can reduce side effects like diarrhea, bladder issues, and skin problems. About 33 adults with locally advanced anal cancer will receive the reduced-dose radiation, and researchers will track their side effects for 90 days after treatment. The goal is to find a way to make treatment easier to tolerate without affecting how well it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Ohio State University Medical Center

Columbus, Ohio, 43210, United States
University of Cincinnati Medical Center

Cincinnati, Ohio, 45219, United States
University of Vermont

Burlington, Vermont, 05405, United States

Conditions

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ANAL CANCER