New combo therapy aims to shrink high-risk rectal tumors before surgery

NCT ID NCT07505472

First seen Apr 03, 2026 · Last updated May 14, 2026 · Updated 6 times

Summary

This study is for people with mid-to-low rectal cancer that has high-risk features. It compares two treatment plans: short-course radiation followed by chemotherapy plus an immunotherapy drug (toripalimab), with or without an additional anti-angiogenic drug (surufatinib). The goal is to see which combination leads to a higher rate of complete tumor disappearance before surgery. About 212 adults aged 18-75 will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • the first hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.