New combo therapy aims to shrink rectal tumors before surgery
NCT ID NCT07528209
First seen Apr 24, 2026 · Last updated Jun 04, 2026 · Updated 6 times
Summary
This phase 3 trial tests whether adding an immunotherapy drug (pucotenlimab) to standard chemotherapy (CAPOX) improves outcomes for people with locally advanced rectal cancer. About 556 adults aged 18-75 will be randomly assigned to receive either the new combination or chemotherapy alone, both with selective radiotherapy if needed. The main goal is to see if the combination extends the time without cancer returning after surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510060, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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