Which Pre-Surgery therapy for rectal cancer causes fewer complications?

NCT ID NCT07346248

First seen Jan 21, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This study looks at 266 adults with advanced rectal cancer to compare how often serious complications happen within 90 days after surgery, depending on the type of treatment they received before surgery. Some patients got standard chemoradiation or short-course radiation, while others got a newer approach called total neoadjuvant treatment (TNT). The goal is to find out which pre-surgery plan leads to fewer problems and better recovery.

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Contacts and locations

Locations

  • IRCCS Humanitas Research Hospital

    Rozzano, Milan, 20089, Italy

Conditions

Explore the condition pages connected to this study.