New drug combo shows promise against advanced rectal cancer

NCT ID NCT02688712

First seen Apr 23, 2026 · Last updated May 16, 2026 · Updated 5 times

Summary

This study tests whether adding the experimental drug LY2157299 to standard chemotherapy and radiation can improve outcomes for people with locally advanced rectal cancer. About 50 adults will receive the combination over 8 weeks, and researchers will track tumor response and immune system changes for up to 5 years. The main goal is to see if the cancer disappears completely after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Providence Cancer Center

    Portland, Oregon, 97213, United States

Conditions

Explore the condition pages connected to this study.