New X-Ray technique could help rectal cancer patients avoid surgery and keep their rectum

NCT ID NCT06402864

First seen Dec 26, 2025 · Last updated May 09, 2026 · Updated 16 times

Summary

This study tests whether adding a precise, high-dose X-ray treatment (contact X-ray brachytherapy) to standard chemotherapy can help people with intermediate-stage rectal cancer keep their rectum and avoid major surgery. About 212 adults with tumors 3.1 to 6 cm in size will be enrolled. The goal is to see if this combination increases the chance of living without needing a permanent colostomy or rectum removal.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Saint Etienne

    RECRUITING

    Saint-Etienne, France, 42270, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, France, 06189, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Léon Bérard

    RECRUITING

    Lyon, France, 69008, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre d'oncologie et de radiothérapie

    RECRUITING

    Mâcon, France, 7100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre de Haute Energie

    RECRUITING

    Nice, France, 06000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre de radiotéhrapie Charcot

    RECRUITING

    Lyon, France, 69110, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Européen

    RECRUITING

    Marseille, France, 13003, France

    Contact Email: •••••@•••••

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, France, 94805, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Sainte Catherine

    RECRUITING

    Avignon, France, 84918, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de cancérologie de l'Ouest

    RECRUITING

    Saint-Herblain, France, 44800, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Orlam-Bayard

    RECRUITING

    Villeurbanne, France, 69100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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