Immunotherapy trial aims to help rectal cancer patients avoid surgery

NCT ID NCT06640049

First seen Nov 17, 2025 · Last updated Apr 08, 2026 · Updated 17 times

Summary

This study is testing whether an immunotherapy drug called dostarlimab can effectively treat certain types of rectal cancer without needing surgery or radiation. It involves 23 Chinese participants with untreated, locally advanced rectal cancer who have specific genetic markers in their tumors. The main goal is to see if the treatment leads to a complete disappearance of cancer that lasts for at least 12 months, potentially allowing patients to preserve their rectum.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NEOPLASMS, RECTAL are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • GSK Investigational Site

    Chengdu, 610041, China

  • GSK Investigational Site

    Chongqing, 400010, China

  • GSK Investigational Site

    Guangzhou, 510060, China

  • GSK Investigational Site

    Guangzhou, 510655, China

  • GSK Investigational Site

    Hangzhou, 310016, China

  • GSK Investigational Site

    Hangzhou, China

  • GSK Investigational Site

    Jinan, 250117, China

  • GSK Investigational Site

    Kunming, 650106, China

  • GSK Investigational Site

    Shanghai, 200032, China

Conditions

Explore the condition pages connected to this study.