New drug combo aims to wipe out rectal cancer before surgery

NCT ID NCT05009069

Summary

This study is testing whether adding a new immunotherapy drug (tiragolumab) to an existing one (atezolizumab) can help eliminate rectal cancer more effectively after patients receive standard chemoradiation. The goal is to see if the drugs can destroy all cancer cells in the removed tumor, which may help prevent the cancer from coming back. About 58 patients with locally advanced rectal cancer will receive either the single drug or the combination before their surgery.

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Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, 100142, China

  • First Hospital of China Medical University

    Shenyang, 110001, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    Hangzhou, 310009, China

  • The Sixth Affiliated Hospital of Sun Yat-sen University

    Guangzhou, 510655, China

  • Zhongshan Hospital Fudan University

    Shanghai, 200032, China

Conditions

Explore the condition pages connected to this study.