New Lab-Grown albumin could ease fluid swelling in liver patients

NCT ID NCT05249374

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested a lab-made version of human serum albumin (r-HSA) in 36 people with cirrhosis and ascites (fluid buildup in the belly). The goal was to check safety, how the body processes the drug, and whether it might help. Participants received one of three doses of r-HSA or standard albumin. Results will show if this new option is safe enough to study further.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Recombinant human serum albumin (r-HSA)

What this could lead to

If successful, this could provide a safer or more reliable alternative to standard albumin for managing fluid buildup in cirrhosis patients.

What could go wrong

This is an early Phase 1 trial with only 36 participants, so safety and effectiveness are not yet proven. The drug may not work better than existing treatments or could have unexpected side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hebei Petro China Central Hospital

    Shijiazhuang, Hebei, 050000, China

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100000, China

  • Pingxiang People's Hospital

    Pingxiang, Jiangxi, 337000, China

  • Shenzhen Protgen Co., Ltd.

    Shenzhen, Guangdong, 100084, China

  • Shenzhen Third People's Hospital

    Shenzhen, Guangdong, 518000, China

  • The First Hospital of Changsha

    Changsha, Hunan, 410005, China

  • Yichun People's Hospital

    Yichun, Jiangxi, 336000, China

  • Yiyang Central Hospital

    Yiyang, Hunan, 413000, China