Could a Lab-Made protein replace donor albumin for liver patients?
NCT ID NCT05858853
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a lab-made version of a blood protein (recombinant human serum albumin) works as well as the standard human-derived version for people with liver cirrhosis and fluid buildup in the belly (ascites). 92 adults took part in a double-blind, randomized trial. The main goal was to see if the lab-made protein raises blood albumin levels just as effectively, which could offer a safer, more reliable supply.
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Contacts and locations
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Locations
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Beijing Ditan Hospital, Capital Medical University
Beijing, Beijing Municipality, 100000, China
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Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, 100000, China
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Beijing YouAn Hospital, Capital Medical University
Beijing, Beijing Municipality, 100000, China
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Central Hospital of Hengyang
Hengyang, Hunan, 421000, China
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Guangzhou Eighth People's Hospital, Guangzhou Medical University (Department of Hepatology)
Guangzhou, Guangdong, 510000, China
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Linfen Central Hospital
Linfen, Shanxi, 041000, China
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Meihekou Central Hospital
Tonghua, Jilin, 135099, China
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People's Hospital of Zhengzhou
Zhengzhou, Henan, 450000, China
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Pingxiang No.2 People's Hospital
Pingxiang, Jiangxi, 337000, China
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Pingxiang People's Hospital
Pingxiang, Jiangxi, 337000, China
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Shandong Public Health Clinical Center
Jinan, Shandong, 250000, China
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Shenzhen Protgen Co., Ltd.
Shenzhen, Guangdong, 518000, China
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Shunde Hospital of Southern Medical University
Foshan, Guangdong, 528000, China
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The Affiliated Hospital of Xiangnan University
Chenzhou, Hunan, 423000, China
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The First Affiliated Hospital of University of South China (Department of Infectious Diseases)
Hengyang, Hunan, 421000, China
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The First Affiliated Hospital of University of South China(Department of Gastroenterology)
Hengyang, Hunan, 421000, China
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The First Hospital of Changsha
Changsha, Hunan, 410005, China
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The First People's Hospital of Changde City (Department of Infectious Diseases)
Changde, Hunan, 415000, China
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The First People's Hospital of Changde City(Department of Gastroenterology)
Changde, Hunan, 415000, China
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The Ninth Hospital of Nanchang
Nanchang, Jiangxi, 330000, China
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The Sixth People's Hospital of Zhengzhou
Zhengzhou, Henan, 450000, China
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Xinyang Central Hospital
Xinyang, Henan, 464000, China
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Yiyang Central Hospital
Yiyang, Hunan, 413000, China
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Yueyang Central Hospital
Yueyang, Hunan, 414000, China
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Zhuzhou Central Hospital
Zhuzhou, Hunan, 412000, China
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