Could a Brain-Zapping implant end resistant migraines?

NCT ID NCT06450444

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This study tests a device called PRIMUS that uses mild electrical pulses to nerves in the head and neck. It is for people with chronic or frequent migraine who have not found relief from at least three preventive drugs. The goal is to see if the device safely reduces the number of migraine days per month.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AZ Delta

    RECRUITING

    Roeselare, West Vlaanderen, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AZ Groeninge

    RECRUITING

    Kortrijk, West Vlaanderen, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AZ Oostende

    RECRUITING

    Ostend, West Vlaanderen, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • AZ Sint Jan Brugge

    RECRUITING

    Bruges, West Vlaanderen, 8000, Belgium

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Erasmus MC Rotterdam

    RECRUITING

    Rotterdam, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Genesis Research Services

    ACTIVE_NOT_RECRUITING

    Broadmeadow, New South Wales, NSW, 2292, Australia

  • Jessa Hasselt

    RECRUITING

    Hasselt, Limburg, 3500, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Private Practice Dr. Sava

    ACTIVE_NOT_RECRUITING

    Saint-Nicolas, Liège, Belgium

  • Resolve Pain

    ACTIVE_NOT_RECRUITING

    Buderim, Queensland, 4556, Australia

  • St. Antonius Nieuwegein

    RECRUITING

    Nieuwegein, Netherlands

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ZAS Antwerpen, Campus Sint-Augustinus

    RECRUITING

    Wilrijk, Antwerpen, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.