New hope for FAP patients: early trial targets dangerous polyps
NCT ID NCT05552755
Summary
This early-stage trial is testing an oral drug called REC-4881 in adults with Familial Adenomatous Polyposis (FAP), a genetic condition that causes many polyps and a high cancer risk. The study aims to see if the drug is safe, how it behaves in the body, and if it can reduce the number and size of polyps in the intestines over 24 weeks. Participants must have had prior colon surgery and have a specific genetic diagnosis for the main part of the study.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Locations
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Benaroya Research Institute at Virginia Mason
RECRUITINGSeattle, Washington, 98101, United States
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Corewell Health (Spectrum Health Hospitals Colorectal Cancer Multis)
RECRUITINGGrand Rapids, Michigan, 49503, United States
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Del Sol Research Management
WITHDRAWNTucson, Arizona, 85715, United States
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Digestive and Liver Center of Florida
ACTIVE_NOT_RECRUITINGOrlando, Florida, 32825, United States
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GI Pros
WITHDRAWNNaples, Florida, 34102, United States
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Gastro One-8110 Walnut Rs
ACTIVE_NOT_RECRUITINGCordova, Tennessee, 38108, United States
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Gastroenterology Health Partners, PLLC
WITHDRAWNNew Albany, Indiana, 47150, United States
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Genetic Cancer Prevention Clinic - UT Southwestern
RECRUITINGDallas, Texas, 75390, United States
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Huntsman Cancer Institute and University of Utah
RECRUITINGSalt Lake City, Utah, 84112, United States
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Mayo Clinic - Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Mayo Clinic - Scottsdale
ACTIVE_NOT_RECRUITINGScottsdale, Arizona, 85259, United States
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Medical Associates Research Group
WITHDRAWNSan Diego, California, 92123, United States
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Tandem Clinical Research
TERMINATEDMarrero, Louisiana, 70072, United States
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Vanderbilt Digestive Center
RECRUITINGNashville, Tennessee, 37232, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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Conditions
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