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Could a simple exercise program rewire emotional control in depression?

NCT ID NCT07780695

Symptom relief Sponsor: Centre Hospitalier Georges Mazurelle Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 21, 2026 · Last updated Aug 25, 2026 · Updated 2 times

Summary

This trial tests whether a structured, adapted physical activity program can improve emotion regulation in adults with depressive disorders who have recently been discharged from psychiatric hospitalization. Participants are randomly assigned to either a standard exercise program or one that also includes activities specifically targeting emotional regulation. The study measures changes in emotion regulation strategies, as well as depressive symptoms, anxiety, and self-esteem, to see if exercise offers a valuable complement to usual care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Adapted physical activity program (standard or combined with emotion-regulation activities)
What this could lead to
If effective, this could point toward a non-drug approach to help people with depression better manage their emotions after hospitalization.
What could go wrong
This is a small, early-stage trial, so results may not be conclusive or widely applicable. The program requires physical effort, which may be challenging for some participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

45 people

The number who actually took part.

Started

Feb 2023

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age over 18 years * Unipolar or bipolar depressive disorder * Discharged from full hospitalization, up to three weeks after discharge * Able to provide free and informed consent * Not participating in any other research Exclusion Criteria: * High suicidal risk, at the investigator's discretion * Medical contraindication to any physical activity * Motor, psychological, or intellectual disability, or other medical condition, at the investigator's discretion, preventing full participation in the study * Severe addictive disorder impeding participation in the study * Psychotic disorder * Pregnancy or breastfeeding * Any circumstances rendering the participant unable to understand the nature, purpose, or consequences of the trial * Under legal protection (guardianship or trusteeship) * No social security coverage

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Conditions

The condition(s) this trial relates to.

depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Depressive disorder

Contacts and locations

Locations

  • EPSM de Vendée - Centre Hospitalier Georges Mazurelle

    La Roche-sur-Yon, Vendée, 85 000, France

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