New combo offers hope for aggressive lymphoma in diverse patients

NCT ID NCT04981795

First seen May 07, 2026 · Last updated Jun 17, 2026 · Updated 8 times

Summary

This study tracked 102 US adults with relapsed or refractory diffuse large B-cell lymphoma (a type of blood cancer) who were treated with a combination of tafasitamab and lenalidomide. The goal was to see how safe and effective this treatment is, especially for racial and ethnic minority patients. Researchers measured side effects, tumor shrinkage, and how long patients lived without the cancer getting worse.

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Contacts and locations

Locations

  • Alabama Oncology

    Birmingham, Alabama, 35211, United States

  • American Oncology Partners of Maryland PA

    Bethesda, Maryland, 20817, United States

  • Clearview Cancer Institute

    Huntsville, Alabama, 35805, United States

  • Duke University

    Durham, North Carolina, 27705, United States

  • Froedtert & Medical College Clinics

    Milwaukee, Wisconsin, 53226, United States

  • Henry Ford Health System

    Detroit, Michigan, 48202, United States

  • Integris Cancer Institute of Oklahoma

    Oklahoma City, Oklahoma, 73142, United States

  • Lankenau Medical Center

    Wynnewood, Pennsylvania, 19096, United States

  • Leo Jenkins Cancer Center/ECU School of Medicine

    Greenville, North Carolina, 27858, United States

  • Levine Cancer Institute

    Charlotte, North Carolina, 28204, United States

  • McFarland Clinic P.C.

    Ames, Iowa, 50010, United States

  • Mercy Medical Center

    Canton, Ohio, 44708, United States

  • Mission Cancer and Blood

    Des Moines, Iowa, 50309, United States

  • Morristown Medical Center

    Morristown, New Jersey, 07960-6136, United States

  • Ohio Health Marion Area Physicians

    Marion, Ohio, 43302, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903-2681, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • Tri County Hematology & Oncology Associates, Inc

    Massillon, Ohio, 44646, United States

  • Tulane Cancer Center

    New Orleans, Louisiana, 70112, United States

  • UW Medicine

    Seattle, Washington, 98109, United States

  • University of California, Irvine Medical Center

    Orange, California, 92868, United States

  • University of Michigan Comprehensive Cancer Center Michigan Medicine

    Ann Arbor, Michigan, 48109, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • VA Medical Center - Durham

    Durham, North Carolina, 27705, United States

  • Westchester Medical Center

    Hawthorne, New York, 10532, United States

  • Yakima Valley Memorial Hospital/North Star Lodge

    Yakima, Washington, 98902, United States

Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma lymphoma relapsed/refractory diffuse large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.