Stem cell infusion could be lifeline for ICU patients with lung failure

NCT ID NCT03042143

First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 28 times

Summary

This study tests whether a single infusion of mesenchymal stem cells (MSCs) can help treat acute respiratory distress syndrome (ARDS), a severe lung condition common in ICU patients, including those with COVID-19. About 129 adults on ventilators will first receive different doses to find a safe amount, then be randomly assigned to get MSCs or a placebo. The goal is to see if MSCs improve lung function and reduce complications.

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Contacts and locations

Locations

  • Belfast Health and Social Care Trust, Royal Hospitals

    Belfast, Northern Ireland, BT12 6BA, United Kingdom

Conditions

Explore the condition pages connected to this study.