Can blood tests and scans track lymphoma in real time? new study aims to find out.

NCT ID NCT07514715

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will test whether doctors can quickly and accurately monitor minimal residual disease (tiny amounts of cancer left after treatment) in people with aggressive B-cell lymphoma. Researchers will use blood tests to look for tumor DNA and PET scans to see if results can be delivered within strict time limits. The goal is to see if this real-time monitoring approach is feasible, not to test a new treatment. About 129 participants will be enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
blood test for ctDNA analysis
What this could lead to
If successful, this could enable doctors to track cancer more accurately during treatment, potentially leading to better-tailored therapies.
What could go wrong
This is an early feasibility study, not testing a new treatment. It may show that real-time monitoring is not practical or does not improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CENTRE HENRI BECQUEREL - Service Hématologie

    Rouen, 76038, France

  • CENTRE LEON BERARD - Service Hématologie

    Lyon, 69373, France

  • CH D'AVIGNON - HOPITAL HENRI DUFFAUT - Service d'Onco-Hématologie

    Avignon, 84000, France

  • CH DE VERSAILLES - HOPITAL ANDRE MIGNOT - Service Hématologie Adolescents et Jeunes Adultes

    Le Chesnay, 78157, France

  • CHD DE VENDEE - Service Hématologie

    La Roche-sur-Yon, 85925, France

  • CHRU NANCY - HÔPITAL BRABOIS - Service Hématologie

    Vandœuvre-lès-Nancy, 54511, France

  • CHU D'AMIENS - HOPITAL SUD - Service Hématologie Clinique et Thérapie Cellulaire

    Amiens, 80054, France

  • CHU D'ANGERS - Service des Maladies du Sang

    Angers, 49033, France

  • CHU DE BORDEAUX - HOPITAL HAUT-LEVEQUE - CENTRE FRANCOIS MAGENDIE - Service d'Hématologie et Thérapie Cellulaire

    Pessac, 33604, France

  • CHU DE GRENOBLE - Service Hématologie

    La Tronche, 38700, France

  • CHU DE LILLE - HOPITAL CLAUDE HURIEZ - Service des Maladies du Sang

    Lille, 59037, France

  • CHU DE MONTPELLIER - Département d'Hématologie Clinique

    Montpellier, 34295, France

  • CHU DE NANTES - Service Hématologie

    Nantes, 44093, France

  • CHU DE POITIERS - HOPITAL DE LA MILETRIE - Service d'Oncologie Hématologique et Thérapie Cellulaire

    Poitiers, 86021, France

  • CHU DE REIMS - HOPITAL ROBERT DEBRE - Service Hématologie

    Reims, 51092, France

  • CHU DIJON BOURGOGNE - Service Hématologie Clinique

    Dijon, 21000, France

  • CHU ESTAING - Service Thérapie Cellulaire et Hématologie Clinique

    Clermont-Ferrand, 63003, France

  • CHU JEAN MINJOZ - Service Hématologie

    Besançon, 25030, France

  • CHU LYON-SUD - Hématologie Clinique

    Pierre-Bénite, 69495, France

  • CHU ORLEANS - Service Oncologie Médicale

    Orléans, 45067, France

  • CHU PONTCHAILLOU - Hématologie Clinique

    Rennes, 35033, France

  • GUSTAVE ROUSSY CANCER CAMPUS GRAND PARIS - Département Médecine Oncologique

    Villejuif, 94085, France

  • HOPITAL COCHIN - Hématologie clinique

    Paris, 75014, France

  • HOPITAL DE LA PITIE SALPETRIERE - Service Hématologie Clinique

    Paris, 75651, France

  • HOPITAL HENRI MONDOR - Unité Hémopathies Lymphoïdes

    Créteil, 94010, France

  • HOPITAL NECKER - Service Hématologie Adultes

    Paris, 75743, France

  • HOPITAL SAINT VINCENT-DE-PAUL - Service Hématologie Clinique

    Lille, 59020, France

  • HOPITAL SAINT-LOUIS - Service Hématologie Adolescents et Jeunes Adultes

    Paris, 75475, France

  • INSTITUT CURIE - SITE SAINT-CLOUD - Service Hématologie

    Saint-Cloud, 92210, France

  • IUCT ONCOPOLE - Service Hématologie

    Toulouse, 31059, France

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