Can blood tests and scans track lymphoma in real time? new study aims to find out.

NCT ID NCT07514715

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will test whether doctors can quickly and accurately monitor minimal residual disease (tiny amounts of cancer left after treatment) in people with aggressive B-cell lymphoma. Researchers will use blood tests to look for tumor DNA and PET scans to see if results can be delivered within strict time limits. The goal is to see if this real-time monitoring approach is feasible, not to test a new treatment. About 129 participants will be enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

blood test for ctDNA analysis

What this could lead to

If successful, this could enable doctors to track cancer more accurately during treatment, potentially leading to better-tailored therapies.

What could go wrong

This is an early feasibility study, not testing a new treatment. It may show that real-time monitoring is not practical or does not improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aggressive B-cell non-Hodgkin lymphoma diffuse large B-cell lymphoma follicular lymphoma high grade B-cell lymphoma high grade B-cell lymphoma with MYC and/ or BCL2 and/or BCL6 rearrangement marginal zone lymphoma Neoplasm, Residual primary mediastinal large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CENTRE HENRI BECQUEREL - Service Hématologie

    Rouen, 76038, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CENTRE LEON BERARD - Service Hématologie

    Lyon, 69373, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH D'AVIGNON - HOPITAL HENRI DUFFAUT - Service d'Onco-Hématologie

    Avignon, 84000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CH DE VERSAILLES - HOPITAL ANDRE MIGNOT - Service Hématologie Adolescents et Jeunes Adultes

    Le Chesnay, 78157, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHD DE VENDEE - Service Hématologie

    La Roche-sur-Yon, 85925, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHRU NANCY - HÔPITAL BRABOIS - Service Hématologie

    Vandœuvre-lès-Nancy, 54511, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU D'AMIENS - HOPITAL SUD - Service Hématologie Clinique et Thérapie Cellulaire

    Amiens, 80054, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU D'ANGERS - Service des Maladies du Sang

    Angers, 49033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU DE BORDEAUX - HOPITAL HAUT-LEVEQUE - CENTRE FRANCOIS MAGENDIE - Service d'Hématologie et Thérapie Cellulaire

    Pessac, 33604, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU DE GRENOBLE - Service Hématologie

    La Tronche, 38700, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU DE LILLE - HOPITAL CLAUDE HURIEZ - Service des Maladies du Sang

    Lille, 59037, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU DE MONTPELLIER - Département d'Hématologie Clinique

    Montpellier, 34295, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU DE NANTES - Service Hématologie

    Nantes, 44093, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU DE POITIERS - HOPITAL DE LA MILETRIE - Service d'Oncologie Hématologique et Thérapie Cellulaire

    Poitiers, 86021, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU DE REIMS - HOPITAL ROBERT DEBRE - Service Hématologie

    Reims, 51092, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU DIJON BOURGOGNE - Service Hématologie Clinique

    Dijon, 21000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU ESTAING - Service Thérapie Cellulaire et Hématologie Clinique

    Clermont-Ferrand, 63003, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU JEAN MINJOZ - Service Hématologie

    Besançon, 25030, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU LYON-SUD - Hématologie Clinique

    Pierre-Bénite, 69495, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU ORLEANS - Service Oncologie Médicale

    Orléans, 45067, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU PONTCHAILLOU - Hématologie Clinique

    Rennes, 35033, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • GUSTAVE ROUSSY CANCER CAMPUS GRAND PARIS - Département Médecine Oncologique

    Villejuif, 94085, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOPITAL COCHIN - Hématologie clinique

    Paris, 75014, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOPITAL DE LA PITIE SALPETRIERE - Service Hématologie Clinique

    Paris, 75651, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOPITAL HENRI MONDOR - Unité Hémopathies Lymphoïdes

    Créteil, 94010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOPITAL NECKER - Service Hématologie Adultes

    Paris, 75743, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOPITAL SAINT VINCENT-DE-PAUL - Service Hématologie Clinique

    Lille, 59020, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HOPITAL SAINT-LOUIS - Service Hématologie Adolescents et Jeunes Adultes

    Paris, 75475, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • INSTITUT CURIE - SITE SAINT-CLOUD - Service Hématologie

    Saint-Cloud, 92210, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • IUCT ONCOPOLE - Service Hématologie

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••