Can thinking shrink depression? new Brain-Feedback study tests mind over mood
NCT ID NCT06050070
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a technique called real-time fMRI neurofeedback, where people with depression learn to control brain activity by watching a visual pattern change in real time during an MRI scan. Researchers want to see if this can help regulate brain networks linked to depression. The trial involves 58 adults with major depressive disorder and is funded by the National Institutes of Health.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
real-time fMRI neurofeedback
What this could lead to
If successful, this could point toward a non-drug technique to help people with depression better control brain activity and manage symptoms.
What could go wrong
This is a very early, small study (58 people) testing feasibility, not treatment. It may not lead to any clinical benefit, and results may not apply to all depression patients.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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