New drug RC278 targets Hard-to-Treat solid tumors in early trial
NCT ID NCT07105215
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called RC278 in people with advanced solid tumors that cannot be removed by surgery or have spread. The main goals are to find a safe dose and see if the drug can shrink tumors. About 312 adults aged 18 to 75 with good overall health are being recruited.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Anyang Cancer Hospital
RECRUITINGLuoyan, Henan, China
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Cancer Hospital Chinese Academy of Medical Sciences
RECRUITINGBeijing, Beijing Municipality, China
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Cancer Hospital of Shandong First Medical University
RECRUITINGJinan, China
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Fudan University Shanghai Cancer Center
RECRUITINGShanghai, Shanghai Municipality, China
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Fujian Cancer Hospital
RECRUITINGFuzhou, Fujian, China
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Fujian Cancer Hospital
RECRUITINGFuzhou, Fujian, China
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Fujian Medical University Union Hospital
RECRUITINGFuzhou, Fujian, China
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Guangxi Medical University Cancer Hospital & Guangxi Cancer Institute
RECRUITINGNanning, Guangxi, China
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Harbin Medical University Cancer Hospital
RECRUITINGHarbin, Heilongjiang, China
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Henan Cancer Hospital
RECRUITINGZhengzhou, China
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Hubei Cancer Hospital
RECRUITINGWuhan, Hubei, China
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Hunan Cancer Hospital
RECRUITINGChangsha, Hunan, China
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Hunan Cancer Hospital
RECRUITINGChangsha, Hunan, China
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Hunan Cancer Hospital
RECRUITINGChangsha, Hunan, China
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Hunan Cancer Hospital
RECRUITINGChangsha, Hunan, China
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Jiangsu Province Hospital
RECRUITINGNanjing, Jiangsu, China
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Jinan Central Hospital
RECRUITINGJinan, China
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Liaoning Cancer Hospital & Institute
RECRUITINGShenyang, Liaoning, China
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Nanyang Second General Hospital
RECRUITINGNanyang, Henan, China
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Shanxi Cancer Hospital
RECRUITINGTaiyuan, China
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Sir Run Run Shaw Hospital, affiliated with Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, China
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Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, China
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Taizhou Hospital of Zhejiang Province
RECRUITINGTaizhou, Zhejiang, China
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The Affiliated Hospital of Xuzhou Medical University
RECRUITINGXuzhou, Jiangsu, China
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The First Affiliated Hospital of Henan University of Science &Technology
RECRUITINGLuoyang, Henan, China
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The First Affiliated Hospital of Nanchang University
RECRUITINGNanchang, Jiangxi, China
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The First Affiliated Hospital of Xiamen University
RECRUITINGXiamen, Fujian, China
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The First Affiliated Hospital of Xinxiang Medical University
RECRUITINGXinxiang, Henan, China
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The First Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, Henan, China
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The First Affiliated Hospital, Zhejiang University School Of Medicine
RECRUITINGHangzhou, China
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The Second Affiliated Hospital of Guilin Medical University
RECRUITINGGuilin, Guangxi, China
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The first Hospital of China Medical University
RECRUITINGShenyang, Liaoning, China
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Tongji Hospital, Tongji Medical College of HUST, China
RECRUITINGWuhan, Hubei, China
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, China
RECRUITINGWuhan, Hu'Nan, China
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West China Hospital of Sichuan University
RECRUITINGChengdu, Sichuan, China
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Xuzhou Central Hospital
RECRUITINGXuzhou, Jiangsu, China
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Yunnan Tumor Hospital
RECRUITINGKunming, Yunnan, China
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Zhejiang Cancer Hospital
RECRUITINGHangzhou, Zhejiang, China
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Zhongshan Hospital, Fudan University
RECRUITINGShanghai, Shanghai Municipality, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Dual-Pronged antibody outsmart advanced solid tumors?
- Can a new infusion drug shrink Hard-to-Treat tumors?
- Can engineered immune cells target a common ovarian cancer protein?
- Can a new imaging tracer outperform standard scans in finding hidden tumors?
- Spinal injection of dual immunotherapy plus chemotherapy targets cancer spread to brain lining
- Lab-Made immune protein takes on advanced cancers in first human test