New shot aims to cut COPD attacks in half?
NCT ID NCT07402551
First seen Jun 26, 2026 · Last updated Jul 10, 2026 · Updated 3 times
Summary
This Phase 2 trial tests an injection called RC1416 in 180 people with moderate to severe COPD. Participants will receive either the drug or a placebo to see if it reduces serious flare-ups and improves lung function over time. The study is double-blind, meaning neither patients nor doctors know who gets the real drug.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- RC1416 injection
- What this could lead to
- If successful, RC1416 could become a new treatment option to reduce COPD exacerbations and help patients breathe better.
- What could go wrong
- This is an early Phase 2 trial with only 180 participants, so results may not apply to everyone. The drug may not work better than placebo or could cause side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Hospital of Zunyi Medical University
RECRUITINGZunyi, Guizhou, 563000, China
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Anhui Provincial Chest Hospital
RECRUITINGHefei, Anhui, 230031, China
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Anyang People's Hospital
RECRUITINGAnyang, Henan, 455000, China
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Chengdu Fifth People's Hospital
RECRUITINGChengdu, Sichuan, 611130, China
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Guangzhou Medical University Affiliated Qingyuan Hospital (Qingyuan People's Hospital)
RECRUITINGQingyuan, Guangdong, 511518, China
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Huizhou Third People's Hospital
RECRUITINGHuizhou, Guangdong, 516002, China
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Jiangmen Central Hospital
RECRUITINGJiangmen, Guangdong, 529000, China
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Jiaozuo Second People's Hospital
RECRUITINGJiaozuo, Henan, 454000, China
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Jiu Jiang NO.1 People's Hospital
RECRUITINGJiujiang, Jiangxi, 332000, China
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LiaoCheng People's Hospital
RECRUITINGLiaocheng, Shandong, 252000, China
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Loudi Central Hospital
RECRUITINGLoudi, Hunan, 417000, China
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Mianyang central hospital
RECRUITINGMianyang, Sichuan, 621099, China
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Nanjing First Hospital
RECRUITINGNanjing, Jiangsu, 210006, China
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Nanyang First People's Hospital
RECRUITINGNanyang, Henan, 473000, China
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Nanyang Second People's Hospital
RECRUITINGNanyang, Henan, 473000, China
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People's Hospital of Pingxiang City
RECRUITINGPingxiang, Jiangxi, China
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Qingdao Municipal Hospital
RECRUITINGQingdao, Shandong, 266000, China
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Sanmenxia Central Hospital
RECRUITINGSanmenxia, Henan, 472000, China
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Shanghai Pulmonary Hospital
RECRUITINGShanghai, Shanghai Municipality, 200433, China
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Shengjing Hospital of China Medical University
RECRUITINGShenyang, Liaoning, 110004, China
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Suining Central Hospital
RECRUITINGSuining, Sichuan, 629000, China
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The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU
RECRUITINGWenzhou, Zhejiang, 325035, China
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The Affiliated Bishan Hospital of Chongqing Medical University
RECRUITINGChongqing, Chongqing Municipality, 402760, China
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The Affiliated Hospital of Inner Mongolia Medical University
RECRUITINGHohhot, Inner Mongolia, 010030, China
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The First Affiliated Hospital of Jinan University
RECRUITINGGuangzhou, Guangdong, 510000, China
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The First Affiliated Hospital of guangxi Medical University
RECRUITINGNanning, Guangxi, 530021, China
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The First People's Hospital of Hangzhou (Westlake University Affiliated The First People's Hospital of Hangzhou)
NOT_YET_RECRUITINGHangzhou, Zhejiang, 310006, China
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The First People's Hospital of Lianyungang City
RECRUITINGLianyungang, Jiangsu, 222061, China
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The First People's Hospital of Yulin
RECRUITINGYulin, Guangxi, 537000, China
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The Second Hospital of Jilin University
RECRUITINGChangchun, Jilin, 130041, China
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The Second People's Hospital of Weifang
RECRUITINGWeifang, Shandong, 261041, China
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The Third People's Hospital of Chengdu City
RECRUITINGChengdu, Sichuan, 610031, China
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The first affiliated hospital of guangzhou medical university
RECRUITINGGuangzhou, Guangdong, 510000, China
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The first affiliated hospital of guangzhou medical university
RECRUITINGGuangzhou, Guangdong, China
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Wan Bei General Hospital of Wanbei Coal power Group
RECRUITINGSuzhou, Anhui, 234000, China
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Xinxiang First People's Hospital
RECRUITINGXinxiang, Henan, 453000, China
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Xuzhou Central Hospital
RECRUITINGXuzhou, Jiangsu, 221009, China
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Yangzhou University Affiliated Hospital
RECRUITINGYangzhou, Jiangsu, 225012, China
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Yichang Central People's Hospital
RECRUITINGYichang, Hubei, 443000, China
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Zhongshan Hospital Xiamen University
RECRUITINGXiamen, Fujian, 361004, China
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Zibo Municipal Hospital
RECRUITINGZibo, Shandong, 255499, China
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Zigong First People's Hospital Zigong Academy of Medicalsciences
RECRUITINGZigong, Sichuan, 643000, China
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Other studies related to the condition(s) this trial covers.