Breakthrough drug shows promise in halting debilitating neurological attacks

NCT ID NCT04201262

Summary

This Phase 3 clinical trial tested whether the drug ravulizumab could safely prevent relapses in adults with neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune disease that attacks the spinal cord and optic nerves. The study involved 58 participants and compared outcomes to an external placebo group. The main goal was to see if the treatment reduced the number of disease flare-ups and slowed disability progression.

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Contacts and locations

Locations

  • Research Site

    Aurora, Colorado, 80045, United States

  • Research Site

    Fort Collins, Colorado, 80528, United States

  • Research Site

    Washington D.C., District of Columbia, 20007, United States

  • Research Site

    Miami, Florida, 33136, United States

  • Research Site

    Boston, Massachusetts, 02114, United States

  • Research Site

    Rochester, Minnesota, 55905, United States

  • Research Site

    Jackson, Mississippi, 39216, United States

  • Research Site

    St Louis, Missouri, 63110, United States

  • Research Site

    Cincinnati, Ohio, 45219, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    Camperdown, 2050, Australia

  • Research Site

    Fitzroy, 3065, Australia

  • Research Site

    Vienna, 1090, Austria

  • Research Site

    Burnaby, British Columbia, V5G 2X6, Canada

  • Research Site

    Aarhus, 8200, Denmark

  • Research Site

    Strasbourg, 67098, France

  • Research Site

    Berlin, 10117, Germany

  • Research Site

    Leipzig, 04103, Germany

  • Research Site

    München, 81675, Germany

  • Research Site

    Cefalù, 90015, Italy

  • Research Site

    Gallarate, 21013, Italy

  • Research Site

    Naples, 80131, Italy

  • Research Site

    Roma, 00133, Italy

  • Research Site

    Rome, 00178, Italy

  • Research Site

    Chiba, 260-0877, Japan

  • Research Site

    Fukuoka, 812-8582, Japan

  • Research Site

    Kawagoe-shi, 350-8550, Japan

  • Research Site

    Niigata, 951-8585, Japan

  • Research Site

    Sendai, 980-8574, Japan

  • Research Site

    Sendai, 983-8512, Japan

  • Research Site

    Katowice, 40-571, Poland

  • Research Site

    Lódz, 90-324, Poland

  • Research Site

    Goyang-si, 10408, South Korea

  • Research Site

    Seoul, 02841, South Korea

  • Research Site

    Seoul, 03722, South Korea

  • Research Site

    Seoul, 06351, South Korea

  • Research Site

    Seoul, 143-729, South Korea

  • Research Site

    Barcelona, 08036, Spain

  • Research Site

    Madrid, 28040, Spain

  • Research Site

    Málaga, 29010, Spain

  • Research Site

    Oxford, OX3 9DU, United Kingdom

Conditions

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